| Bile acid |
| LIPID_ID | BA0530 |
| CHEM_NA | 2-(S)-[2-[3¦Á-HYDROXY-12¦Á-(2-(S)-METHYL-1- |
| OXOBUTOXY)-5¦Â-ANDROSTAN-17¦Â-YL]ETHYL]- |
| TETRAHYDRO-4-(S)-HYDROXY-2H-PYRAN-6-ONE |
| COMMON_NA |
| MOL_FORMULA | C31H50O6 |
| MOL_WT | 518 |
| MELT_PT |
| BOIL_PT |
| OPT_ROT |
| REFRA_IND |
| DENSITY |
| SOLUBILITY |
| UV_SPEC |
| IR_SPEC |
| NMR_SPEC | 1H-NMR(CDCl3) 0.64(s,3H), 0.90(s,3H), |
| 0.91(t,3H,J=7Hz), 1.16(d,3H,J=7Hz), 2.40(m,1H), |
| 2.59(m,1H), 2.72(dd,1H,J1=16Hz,J2=6Hz), |
| 3.55-3.68(m,1H), 4.32-4.39(m,1H), 4.52-4.62(m,1H), |
| 4.94-4.98(m,1H)(215) |
| MS_SPEC | M/Z (FAB) 525.4(M+Li)(215) |
| NOTE_SPEC |
| SOURCE |
| BIOL_ACTIV | HMG-CoA REDUCTASE INHIBITOR ON |
| CHOLESTEROL BIOSYNTHESIS IN Hep G2 CELLS |
| IC50-Value : 3x10-5M (215/216) |
| NOTE | SYNTHESIS AND BIOLOGICAL ACTIVITY OF BILE |
| ACID-DERIVED HMG-CoA REDUCTASE |
| INHIBITORS(215) |
| 1998ǯ10·î26Æü | 559 / 591 ¥Ú¡¼¥¸ |