| Prostanoid |
| LIPID_ID | PR0035 |
| CHEM_NA | 7-[3(R)-HYDROXY-2(R)-(3(S)-HYDROXY-1(E)-OCTE |
| NYL)-5-OXOCYCLOPENTAN-1(R)-YL]- |
| 6-OXOHEPTANOIC ACID |
| COMMON_NA | 6-KETO-PROSTAGLANDIN E1 |
| MOL_FORMULA | C20H32O6 |
| MOL_WT | 368 |
| MELT_PT | 65ﾟC (070) |
| BOIL_PT |
| OPT_ROT | [α]20/D -50ﾟ C1.55 METHANOL (070) |
| REFRA_IND |
| DENSITY |
| SOLUBILITY | METHANOL,CHLOROFORM(070) |
| UV_SPEC |
| IR_SPEC | (KBr): ν3400,1740,1720,1710,1245,1160,1075,970 |
| cm-1 (070) |
| NMR_SPEC | 1H-NMR(CD3OD):δ5.58(m,2H,13,14-CH),4.09(m,1H,1 |
| 1-CH),4.02(m,1H,15-CH),2.7 |
| (2H,7-CH),2.69(IH,10β-CH),2.45-2.47(m,3H,5,8,12-C |
| H),2.29(1H,10α-CH), |
| 2.28(2H,2-CH),1.58〜1.32(12H),0.91(t,3H,20-CH3) |
| (092)METHYL |
| MS_SPEC | DIRECT EXPOSURE AMMONIA CI: POSITIVE:386(M+ |
| +18),368(M+),351,350,244,136NEGATIVE:368(M+),350 |
| ,338,332(071) |
| NOTE_SPEC |
| SOURCE | 動物の肝臓などで，PGI2あるいは6ｰｹﾄｰPGF1αから生 |
| 合成する酵素が報告されている． |
| BIOL_ACTIV | 血管拡張，血小板凝集抑制 |
| NOTE |
| 1998年7月17日 | 13 / 70 ページ |