| Prostanoid |
| LIPID_ID | PR0029 |
| CHEM_NA | 5(S)-HYDROXY-6(R)-S-CYSTEINYLICOSA-7(E),9(E), |
| 11(Z),14(Z)-TETRAENOIC ACID |
| COMMON_NA | LEUKOTRIENE E4 |
| MOL_FORMULA | C23H37O5NS |
| MOL_WT | 439 |
| MELT_PT |
| BOIL_PT |
| OPT_ROT | DIMETHYL ESTER [α]20/D +35.2ﾟ (079) |
| REFRA_IND |
| DENSITY |
| SOLUBILITY | METHANOL (079/080) |
| UV_SPEC | 270(ε40000),280(49400),291nm(40000)(080) |
| IR_SPEC |
| NMR_SPEC | DIMETHYL |
| ESTER:1H-NMR(CDCl3):δ6.33(dd,J=14.5,10Hz,1H,10 |
| CH),6.0(t,J=10Hz, |
| 1H,11-CH)5.62(dd,J=14.4,9.6Hz,1H,7-CH),5.3(m,J=10, |
| 9Hz,1H,14-CH),3.71 AND |
| 3.62(2S,6H,OCH3)3.65(m,1H,5-CH),3.4(m,1H,6-CH),2. |
| 95(t,J=9Hz,2H,13-CH),2.02(m,2H,16-CH),0.86(t,J=6Hz |
| MS_SPEC |
| NOTE_SPEC |
| SOURCE | 動物の白血球，ﾏｸﾛﾌｧｰｼﾞ，肥満細胞，肺，腸管などで |
| ，刺激に応じて新規に合成さ |
| たLTC4が代謝されてLTE4となる． |
| BIOL_ACTIV | 気管支収縮，気道粘液の分泌，血管透過性亢進，腸管 |
| 収縮，血管収縮 |
| NOTE |
| 1998年7月17日 | 65 / 70 ページ |