| Sterol |
| LIPID_ID | ST0378 |
| CHEM_NA | 17-(ACETYLOXY)-9-FLUORO-11β-HYDROXYPREG |
| N-4-ENE-3,20-DIONE; |
| 9-FLUORO-11β,17-DIHYDROXYPREGN-4-ENE-3,20 |
| -DIONE-17-ACETATE; |
| 17α-ACETOXY-9α-FLUORO-11β-HYDROXYPRO |
| GESTERONE; |
| COMMON_NA | FLUROGESTONE ACETATE,SC-9880,CRONOLONE |
| SYNCHRONATE |
| MOL_FORMULA | C23H31O5F |
| MOL_WT | 406 |
| MELT_PT | 266-269ﾟC(BENZEN+PETR ETHER or ETHYL |
| ACETATE+PETR ETHER)(839) |
| BOIL_PT |
| OPT_ROT | [α]20/D=+77.6ﾟ(in CHLOROFORM)(839) |
| REFRA_IND |
| DENSITY |
| SOLUBILITY |
| UV_SPEC | UVmax(METHANOL) : 238nm(ε=17,500)(839) |
| IR_SPEC |
| NMR_SPEC |
| MS_SPEC |
| NOTE_SPEC |
| SOURCE | 16,17α-Epoxy-4,9(11)-Pregnadiene-3,20-dione |
| を酢酸中で Hydriodic acid |
| と反応させる事を出発点として合成する｡ (839) |
| BIOL_ACTIV | ・Progestin活性｡ |
| 家畜で progestational |
| agent(月経前期剤)として発情期調節に用いる｡ |
| Clauberg assay で, 経口で用いた場合, subcutaneous |
| progesterone を1としたら,25の活性があった｡ |
| Oral progesterone |
| と比較すると,その2500倍の活性があり, Norlutin |
| の25倍, |
| NOTE | 分子量 406.50 (839) |
| 化学名：21-(ACETYLOXY)-9-FLUORO-11β,17-DIHY |
| DROXY-16-METHYLENEPREGNA-1,4-DIENE-3,20-DI |
| ONE; |
| 9α-FLUORO-11β,17,21-TRIHYDROXY-16-METHYL |
| ENEPREGNA-1,4-DIENE-3,20-DIONE 21-ACETATE; |
| 9α-FLUORO-16-METHYLENE-Δ1,4-PREGNADIENE |
| -11β,1721-TRIOL-3,20-DIONE 21-ACETATE; |
| 16-METHYLENE-9α-FLUOROPREDNISOLONE |
| 21-ACETATE; |
| 9α-FLUORO-16-METHYLENEPREDNISOLONE |
| 1998年7月17日 | 135 / 486 ページ |