| Sterol |
| LIPID_ID | ST0371 |
| CHEM_NA | 17-(ACETYLOXY)-6α-(TRIFLUOROMETHYL)PREGN |
| -4-ENE-3,20-DIONE/17-HYDROXY-6α-(TRIFLUOR |
| OMETHYL)PREGN-4-ENE-3,20-DIONE ACETATE; |
| 17-ACETOXY-6α-(TRIFLUOROMETHYL)PROGESTE |
| RONE;※備考へ続く |
| COMMON_NA | FLUMEDROXONE ACETATE, WG537, DEMIGRAN |
| MOL_FORMULA | C24H31O4F3 |
| MOL_WT | 440 |
| MELT_PT | 206-207ﾟC(821) |
| BOIL_PT |
| OPT_ROT | [α]20/D=+30ﾟ(821) |
| REFRA_IND |
| DENSITY |
| SOLUBILITY |
| UV_SPEC | UVmax(ETHANOL) : 234nm(ε=15,600)(821) |
| IR_SPEC |
| NMR_SPEC |
| MS_SPEC |
| NOTE_SPEC |
| SOURCE | 17α-ACETOXYPROGESTERONE-3-ETHYL ENOL |
| ETHER を |
| Trifluoroiodomethane-Pyridine中でU.V.照射し,できた |
| 6-TRIFLUOROMETHYL-17α-ACETOXYPREGESTER |
| ONE-3-ETHYL ENOL ETHER |
| BIOL_ACTIV | ORAL PROGESTATIONAL活性(Clauberg |
| assayのMcPhail |
| modificationによる)は,6α-METHYL-17α-ACETOXY |
| PROGESTERONEのRelative |
| NOTE | 分子量 440.51 |
| 17α-ACETOXYPROGESTERONEの６位にα-位 |
| Fluorine,chlorine,又はbromineを導入する事によって,経 |
| 口 Progestational活性の著しい増加が見られる。(821) |
| 「化学名の続き」17-HYDROXY-6α-(TRIFLUOROMET |
| HYL)PROGESTERONE ACETATE; |
| 6α-(TRIFLUOROMETHYL)-17-HYDROXYPROGESTE |
| RONE ACETATE. |
| 1998年7月17日 | 173 / 486 ページ |