| Sterol |
| LIPID_ID | ST0320 |
| CHEM_NA | 11β,17,21-TRIHYDROXY-6,16α-DIMETHYL-2'-PHE |
| NYL-2'H-PREGNA-2,4,6-TRIENO[3,2-C]PYRAZOL-2 |
| 0-ONE |
| 21-ACETATE/1,2,3,3A,3B,7,10,10A,10B,11,12,12A-D |
| ODECAHYDRO-1,11-DIHYDROXY-2,5,10A,12A-TETR |
| AMETHYL-7-PHENYLCYCLOPENTA[7,8]PHENANTHR |
| O[2,3-C]PYRAZOL-1-YL HYDROXYMETHYL KETONE |
| ACETATE/6,16α-DIMETHYL-11β,17α,21-TRIHYD |
| ROXY-2'-PHNYL[3,2-PHNYL[3,2-C]PYRAZOLO-4,6- |
| PREGNADIEN-20-ONE 21-ACETATE |
| COMMON_NA | CORTIVAZOL,MK-650;H3625;ALTIM;DIASTER;DILAST |
| ER;IDALTIM |
| MOL_FORMULA | C32H38O5 |
| MOL_WT | 530 |
| MELT_PT | 160-165ﾟC and 229-230ﾟC(DOUBLE M.P.)(706) |
| BOIL_PT |
| OPT_ROT | [α]23/D=+14ﾟ(CHCl3)(706) |
| REFRA_IND |
| DENSITY |
| SOLUBILITY |
| UV_SPEC | UVmax(METHANOL):283,315nm(ε=15,700, |
| 19,000)(706) |
| IR_SPEC |
| NMR_SPEC |
| MS_SPEC |
| NOTE_SPEC |
| SOURCE | 2-HYDROXYMETHYLENE-17α,20,20,21-BISMETHYL |
| ENEDIOXY-6,16α-DIMETHYL-4,6-PREGNADIENE-11 |
| β-OL-3-ONE の加水分解によって得られる｡ (706) |
| BIOL_ACTIV | Glucocorticoid 作用｡ 抗炎症作用｡ SISTEMIC |
| GRANULOMA で見ると, |
| 9α-FLUORO-16α-METHYL-1,4,6-PREGNATRIENE- |
| 11β,17α,21-TRIOL-3,20-DIONE21-ACETATE(Δ6- |
| DEXAMETHASONE)では150の時, CORTIVAZOL は |
| 551(雄 HOLTZMAN RATS(Ca.125g) |
| に経口投与で毎日一週間与える)｡ |
| ヒトリューマチ痛に対して, HYDROCORTISONE |
| の75倍の 活性を持つ｡ |
| NOTE | 分子量 530.66, (706) |
| 1998年7月17日 | 456 / 486 ページ |