| Sterol |
| LIPID_ID | ST0426 |
| CHEM_NA | 13-ETHYL-17-HYDROXY-18,19-DINOR-17α-PREG |
| N-4-EN-20-YN-3-ONE;13β-ETHYL-17α-ETHYNY |
| L-17β-HYDROXYGON-4-EN-3-ONE; |
| 17α-ETHYNYL-18-HOMO-19-NORTESTOSTERONE |
| COMMON_NA | NORGESTREL,OVRETTE |
| MOL_FORMULA | C21H28O2 |
| MOL_WT | 312 |
| MELT_PT | 203-206ﾟC(954), 205-207ﾟC(948), |
| (-)-FORM,238-242ﾟC(948), |
| BOIL_PT |
| OPT_ROT | (+)FORM,[α]25/D=-42.5ﾟ(CHCl3)(948) |
| (-)FORM,[α]25/D=+40.7ﾟ(CHCl3)(948) |
| REFRA_IND |
| DENSITY |
| SOLUBILITY |
| UV_SPEC | UVmax(ETHANOL):241nm(ε=16,700)(948) |
| IR_SPEC |
| NMR_SPEC |
| MS_SPEC |
| NOTE_SPEC |
| SOURCE | 13β-Ethyl-17α-ethynyl-3-methoxygona-2,5(10)-di |
| en-17β-olか, |
| 13β-ethyl-17α-ethynyl-17α-hydroxygon-5(10)-e |
| n-3-oneから合成できる｡ |
| (-)-Formは,(-)-13β-ethyl-3-hydroxygona-1,3,5(10) |
| -trien-17-oneから合成できる｡ |
| (+)-Formは,(+)-13β-ethyl-3-methoxygona-1,3,5(10) |
| BIOL_ACTIV | 天然において (+)-Formに活性がある事と一致して, |
| (±)又は (+)Formが Progestin活性がある｡ (954) |
| NOTE | 分子量 312.44 |
| (-)-Form,Optical rotatory dispersion測定 (dioxane,C |
| 0.0482, 280) ; [α]/400=-237ﾟ,[α]/362=-707ﾟ, |
| [α]/357=-685ﾟ, [α]/349=-815ﾟ, [α]/335=-262ﾟ, |
| [α]/325=+403ﾟ, [α]/300=+1195ﾟ, [α]/280=+1105ﾟ, |
| [α]/265=+1170ﾟ｡(948) |
| 1998年7月17日 | 98 / 486 ページ |