発表した成果

原著論文

  1. Matsubara K, Suzuki T, Ishiguro A, et al: Development of serum IgM antibodies against superantigens of Staphylococcus aureus and Streptococcus pyogenes in Kawasaki disease. Clin Exp Immunol, 143:427-34, 2006
  2. Murata T, Delprato A, Roy CR, et al: The Legionella pneumophila effector protein DrrA is a Rab1 guanine nucleotide-exchange factor. Nat Cell Biol, 8:971-7, 2006.
  3. Sakai M, Ishiguro A, Sekiguchi K, et al: Age-dependence of diffusion-weighted magnetic resonance imaging findings in maple syrup urine disease encephalopathy. J Comput Assist Tomogr, 29:524-527, 2005.
  4. Yasui K, Baba A, Ishiguro A, et al: Neutrophil-mediated inflammation in respiratory syncytial virus bronchiolitis. Pediatr Int, 47:190-195, 2005.
  5. Kagan JC, Murata T, Roy CR: Analysis of Rab1 recruitment to vacuoles containing Legionella penumophila. Methods Enzymol, 403:71-81, 2005.
  6. Neild A, Murata T, Roy CR: Processing and major histocompatibility complex class II presentation of Legionella pneumophila antigens by infected macrophages. Infect Immun, 73:2336-2343, 2005.
  7. Suzuki T, Ishiguro A, Shimbo T: Transient elevation of interleukin-16 at the initial stage of meningitis in children. Clin Exp Immunol, 131:484-489, 2003.
  8. Ishikawa Y, Sekiguchi K, Akasaka Y, et al: Fibromuscular dysplasia of coronary arteries resulting in myocardial infarction associated with hypertrophic cardiomyopathy in Noonan's syndrome. Hum Pathol, 34:282-4, 2003.
  9. 松浦宏樹,石黒 精,鈴木徹臣など:Carbamazepineにより血小板減少を来たした2症例:thrombopoietinとinterleukin-6値の検討.日小血会誌,16:363-366, 2002.
  10. Ishiguro A, Suzuki Y, Mito M, et al: Elevation of serum thrombopoietin precedes thrombocytosis in acute infections. Br J Haematol, 116:612-618, 2002.
  11. Ohnishi M, Terajima J, Murata T, et al: Genomic diversity of enterohemorrhagic Escherichia coli O157 revealed by whole genome PCR scanning. Proc Natl Acad Sci U S A, 99:17043-17048, 2002.
  12. Murata T, Ohnishi M, Hayashi T, et al: Complete nucleotide sequence of plasmid Rts1: implications for evolution of large plasmid genomes. J Bacteriol, 184:3194-3202, 2002.
  13. Matsubara K, Baba K, Ishiguro A, et al: Early elevation of serum thrombopoietin levels and subsequent thrombocytosis in healthy preterm infants. Br J Haematol, 115:963-968, 2001.
  14. Mwamtemi HH, Koike K, Ishiguro A, et al: An increase in circulating mast cell colony-forming cells in asthma. J Immunol, 166:4672-4677, 2001.
  15. 関口恭子,石北 隆,石黒 精など:ペニシリン耐性肺炎球菌による感染性心内膜炎の一例.小児感染免疫,12:369-372, 2000.
  16. Ikeno K, Koike K, Ishiguro A: Stressful delivery influences circulating thrombopoietin (TPO) levels in newborns: possible role for cortisol in TPO-mpl binding. Early Hum Dev, 58:225-235, 2000.
  17. Ishiguro A, Nakahata T, Matsubara K, et al: Age-related changes in thrombopoietin in children: reference interval for serum thrombopoietin levels. Br J Haematol, 106:884-888, 1999.
  18. Ishikita T, Ishiguro A, Fujisawa K, et al: Carbamazepine-induced thrombocytopenia defined by a challenge test. Am J Hematol, 62:52-55, 1999.
  19. Kobayashi M, Ishiguro A, Nakahata T, et al: Serum granulocyte colony-stimulating factor levels in patients with chronic neutropenia of childhood: modulation of G-CSF levels by myeloid precursor cell mass. Br J Haematol, 105:486-490, 1999.
  20. Hojo M, Morimoto T, Maluccio M, et al: Cyclosporine induces cancer progression by a cell-autonomous mechanism. Nature, 397:530-534, 1999.
  21. Hojo M, Ishiguro A, Shimbo T, et al: Prolonged suppressed thyroid-stimulating hormone levels in hyperthyroidism in a neonate born to a mother with Graves' disease. Acta Paediatr Jpn, 40:483-485, 1998.
  22. Ishiguro A, Ishikita T, Shimbo T, et al: Elevation of serum thrombopoietin precedes thrombocytosis in Kawasaki disease. Thromb Haemost, 79:1096-1100, 1998.
  23. Inaba Y, Ishiguro A, Shimbo T: The production of macrophage inflammatory protein-1α in the cerebrospinal fluid at the initial stage of meningitis of children. Pediatr Res, 42:788-793, 1997.
  24. 宇野久仁子,阿部雅章,石黒 精,稲葉雄二,池田紀子,石北隆,栗田佳江,木田あや子,新保敏和:小児病棟における付き添い入院についての検討:母親に対するアンケート調査より.小児保健研究,56:790-793, 1997.
  25. Ishiguro A, Suzuki Y, Fukushima K, et al: The production of IL-8 in cerebrospinal fluid in aseptic meningitis of children. Clin Exp Immunol, 109:426-430, 1997.
  26. Ishiguro A, Nakahata T, Shimbo T, et al: Effects and serum levels of thrombopoietin in a case of chronic thrombocytopenia with achondroplasia. Int J Haematol, 66:99-102, 1997.
  27. 池田紀子,石黒 精,新保敏和など:気管支喘息児における血清 IL-5値と末梢血単核球からの IL-5の産生.日臨免誌,20:159-165, 1997.
  28. 池田紀子,石黒 精,新保敏和など:気管支喘息児の自律神経症状についての多施設アンケート調査:自律神経症状と喘息の重症度および血清IgE値.日児アレルギー誌,10:478-481, 1996.
  29. 池田紀子,石黒 精,新保敏和など:気管支喘息児の日常生活:鍛錬療法と自律神経症状に関するアンケート調査.日児アレルギー誌,10:448-453, 1996.
  30. Ishiguro A, Suzuki Y, Inaba Y, et al: Production of interleukin 10 in the cerebrospinal fluid in aseptic meningitis of children. Pediatr Res, 40:610-614, 1996.
  31. Ishiguro A, Spirin K, Shiohara M, et al: Id2 expression increases with myeloid differentiation in human myeloid cells. Blood, 87:5225-5231, 1996.
  32. Ishiguro A, Inoue K, Shimbo T, et al: Reference intervals for serum granulocyte colony-stimulating factor levels in children. J Pediatr, 128:208-212, 1996.
  33. Murata T: The trpF nucleotide sequence and its promoter analysis in Pseudomonas aeruginosa. Microbiol Immunol, 40:107-114, 1996.
  34. Ishiguro A, Spirin K, Shiohara M, et al: Expression of Id2 and Id3 mRNA in human lymphocytes. Leukemia Res, 19:989-996, 1995.
  35. 稲葉雄二,石黒 精,鈴木洋子,蜂谷みさを,新保敏和:Ubenimex が急性白血病児の interleukin-6 産生能におよぼす作用の検討.Biotherapy, 9:397-398, 1995.
  36. Fukushima K, Ishiguro A, Shimbo T: Transient elevation of granulocyte colony-stimulating factor levels in cerebrospinal fluid at the initial stage of aseptic meningitis in children. Pediatr Res, 37:160-164, 1995.
  37. 福島啓太郎,石黒 精,新保敏和など:顆粒球コロニー刺激因子の週2回の間歇投与が有効であった慢性良性好中球減少症の1例.日小血会誌,8:426-429, 1994.
  38. 福島啓太郎,石黒 精,新保敏和など:無菌性髄膜炎における髄液中のインターロイキン6の上昇. 炎症, 13:263-268, 1993.
  39. 村田敬寛,石黒 精,青沼架佐賜など:心奇形がないにもかかわらず多血症の認められた18トリソミーの8歳女児例. 日児誌,97:129-133, 1993.
  40. 石黒 精,新保敏和,福島啓太郎など:ダニRAST陽性の気管支喘息児におけるダニ抗原刺激によるcolony-stimulating activityの過剰産生.日臨免誌,16:20-26, 1993.
  41. Ishiguro A, Nakahata T, Shimbo T, et al: Improvement of neutropenia and neutrophil dysfunction by granulocyte colony-stimulating factor in a patient with glycogen storage disease type Ib. Eur J Pediatr, 152: 18-20, 1993.
  42. 石黒 精,新保敏和,高橋比路美など:ダニ抗原刺激による気管支喘息児の末梢血単核球からのGM-CSF産生の亢進.アレルギー,41:1658-1663, 1992.
  43. 福島啓太郎,長沼邦明,矢野秀実など:ムンプス発症後急激な経過で多臓器障害を伴う急性脳症を起こした2例.日児誌,96:2124-2129, 1992.
  44. 石黒 精,中畑龍俊,天野芳郎など:単球によるIn vitro造血抑制が認められた肝炎後再生不良性貧血の1例.臨床血液,33:87-92, 1992.
  45. Ishiguro A, Nakahata T, Koike K, et al: Induction of granulocyte and granulocyte-macrophage colony-stimulating factors from human monocytes stimulated by Fc fragments of human IgG. Br J Haematol, 79:14-21, 1991.
  46. 中村岳征,新保敏和,石黒 精など:リポソーム封入muramyl tripeptideにより刺激されたヒト末梢血単球からのIL 6の産生.Biotherapy, 5:1051-1054, 1991.
  47. Koike K, Nakahata T, Ishiguro A, et al: Interleukin-6 enhances murine megakaryocytopoiesis in serum-free culture. Blood, 75:2286-2291,1990.
  48. Tsuji K, Nakahata T, Ishiguro A, et al: Synergistic action of phorbor ester and interleukin-3 in the induction of connective tissue-type mast cell proliferation. J Immunol, 144:678-684, 1990.
  49. Tsuji K, Nakahata T, Ishiguro A, et al: Effects of interleukin-3 and interleukin-4 on the development of "connective tissue-type" mast cells: Interleukin-3 supports their survival and interleukin-4 triggers and supports their proliferation synergistically with interleukin-3. Blood, 75:421-427, 1990.
  50. Yabuhara A, Yanagisawa M, Murata T, et al: Giant lymph node hyperplasia (Castleman's disease) with spontaneous production of high levels of B-cell differentiation factor activity. Cancer, 63:260-265, 1989.
  51. Koike K, Nakahata T, Ishiguro A, et al: Synergism of BSF-2/interleukin 6 and interleukin 3 on development of multi-potential hemopoietic progenitors in serum-free culture. J Exp Med, 168:879-890, 1988.
  52. Komiyama A, Ishiguro A, Kubo T, et al: Increase in neutrophil counts by purified human urinary colony stimulating factor in chronic neutropenia of childhood. Blood, 71:41-45, 1988.
  53. Ishiguro A: Complement-mediated cytotoxicity against marrow late neutrophilic cells in Kostmann's syndrome. Acta Haematol Jpn, 50:1196-1209, 1987.
  54. Naganuma K, Ishii E, Ishiguro A, et al: Hemopoietic progenitors before and after bone marrow transplantation. Acta Haematol Jpn, 49:852-861, 1986.
  55. Nakahata T, Kobayashi T, Ishiguro A, et al: Extensive proliferation of mature connective-tissue type mast cells in vitro. Nature, 324:65-67, 1986.
  56. Nakahata T, Tsuji K, Ishiguro A, et al: Single-cell origin of human mixed hemopoietic colonies expressing various combination of cell lineages. Blood, 65:1010-1016, 1985.